Two people were killed and 14 wounded as an improvised explosive device went off in the Nahrein district of the northern province of Baglan on Tuesday.
The blast reportedly occurred near a mosque after the Eid al-Fitr prayers, which mark the end of the Islamic holy month of Ramadan.
Footage shows blood on the ground, among debris, and an exploded motorbike.
No responsibility has been claimed for the explosion yet.
On Monday, another blast left at least five people dead and ten injured after a bus carrying government employees was struck by an explosion in Kabul.